Klötze is a town in the Altmarkkreis Salzwedel (district), in Saxony-Anhalt, Germany. It is situated approximately 20 km northwest of Gardelegen, and 35 km northeast of Wolfsburg. It was mentioned first in 1144 with the name Cloetze, which means a wooden block. In January 2010, with the disbanding of the Verwaltungsgemeinschaft ("collective municipality") of Klötze, the town absorbed 11 former municipalities.